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If you go with a high-dose vitamin D supplement, like Life Extension's Vitamin D3 (below), "Take a 25-hydroxy vitamin D blood test after 3 months of supplementation to assess and potentially adjust your dosage. Vitamin D production in the skin under the influence of sunlight (UVB) is maximized at levels of sunlight exposure that do not burn the skin. Symptoms may also include increased hunger, feeling tired, and sores that do not heal. Your optimal blood With this in mind, Life Extension formulated BioActive Folate & Vitamin B12 with some of the most biologically active forms of folate and vitamin B12 to maximize benefits for the heart, brain and GI tract. There is also a stage III clinical trial recruiting to study the influence of high-dose vitamin D3 intake on pancreatic cancer surgery outcomes (NCT03472833). Further metabolism of vitamin D to its major circulating form (25(OH)D) and hormonal form (1,25(OH)2D) takes place in the liver and kidney, respectively, but also in other tissues where the 1,25(OH)2D produced serves a
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