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New York informat healthcare; 2010:82-9. Calcitonin is a hormone that helps regulate calcium and phosphate levels in the body. On the flip side, research shows low levels can contribute to a sluggish brain, poor cognitive development, and trouble learning or retaining information. Naghii MR, Mofid M, Asgari AR, Hedayati M, Daneshpour MS. J Womens Health (Larchmt). Overall the risks of consuming this mineral are thought to be minimal, especially from natural food sources. The amount of boron consumed in people who accidentally consumed boron ranged from 18 to 9,713 mg, and most were children younger than 6 years [46]. Maintains Bones, Joints, Neurons and May Reduce Prostate Cancer Risk National Institutes of Health. Can you take boric acid or boron supplements while pregnant? Last medically reviewed on June 15, 2022. U.S. Department of Agriculture and Agricultural Research Service. Is the ketogenic diet right for autoimmune conditions? While some research has found positive outcomes in boron supplementation for treating yeast infections, much of theresearchis dated, and the quality of the research has been questioned. Sea moss, also known as Irish moss or Chondrus crispus, is a red seaweed that grows off the coasts of Iceland, Ireland, and Canada. J Am Diet Assoc 1991;91:558-68. Boron helps your body retain more calcium and magnesium by reducing the amount of each that's lost through urine. Sea moss is full of rich minerals that help your body function at an optimal level, including calcium, iron, zinc, chromium, magnesium, and iodine. Many supplements are great for working out. Biol Trace Elem Res 2011;144:253-63. This section focuses on three health areas in which boron might be involved: osteoarthritis, bone health, and cancer. Boron is present in foods and beverages as inorganic borates as well as mono- or di-sugar-borate esters, such as calcium fructoborate [14,15]. An observational study in Turkey evaluated two criteria for prostate cancer risk, prostate size and prostate specific antigen (PSA) levels. According to the NIH, there is no data about the negative side effects of high boron intake from food or water sources. Her work is regularly featured in media such as First For Women, Woman's World, and Natural Health. * Breast milk, formula, and food should be the only sources of boron for infants. In one double-blind placebo-controlled study (one in which neither participants nor researchers know who was given the active ingredient or a placebo), people with OA evaluated supplementation of calcium fructoborate (a form of boron) for two weeks. Calcium fructoborate: plant-based dietary boron as potential medicine for cancer therapy. According to some epidemiologic studies, in areas of the world where intake of this mineral is lower (around one milligram or less/day) the incidence of arthritis is significantly higher than in areas where intake is higher (around three to 10 milligrams/day on average). Short-term efficacy of calcium fructoborate on subjects with knee discomfort: a comparative, double-blind, placebo-controlled clinical study. Dosage Examine Database Boron is most often used for Joints & Bones. When researchers compared the effects of low boron intake in healthy adults with higher intake, there was a significant increase in the proportion of low-frequency brain activity and a decrease in the proportion of higher-frequency activity in the group consuming more. Women sometimes use capsules containing boric . Osteoarthritis (OA) occurs when the cartilage that protects bones wears down over time, causing discomfort and pain. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. ( Nielsen 2009, Nielsen 2009) Dietary boron, brain function, and cognitive performance. This communication describes some of the effects of dietary boron on 12 women between the ages of 48 and 82 housed in a metabolic unit. Here, find out why and get some tips on managing the challenges. Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines. Clin Interv Aging 2014;9:895-9. Dietary boron intake and prostate cancer risk. The lack of substantial changes in blood boron levels in response to large increases in dietary intakes suggests that the body maintains boron homeostasis, likely by increasing urinary excretion, but the regulatory mechanisms for boron homeostasis have not been identified [6]. Treatment of vaginitis caused by Candida glabrata: use of topical boric acid and flucytosine. Instead, authorities have determined an upper limit for boron, which indicates amounts that most people can consume while maintaining their health without experiencing signs of deficiency or toxicity. Intake recommendations for nutrients are provided in the Dietary Reference Intakes (DRIs) developed by an expert committee of the Food and Nutrition Board (FNB) at the National Academies of Sciences, Engineering, and Medicine [2]. Several observational studies found that boron intakes are inversely associated with prostate cancer risk in men and with lung and cervical cancer risk in women [1,9,41-44]. Its also found in water to some degree, although we get most of our boron from foods in our diets. Menopause and depression: Is there a link? Boron is excreted mainly in the urine, and small amounts are excreted in the feces, sweat, breath, and bile [9,10]. According to the NIH, a low-boron diet may affect postmenopausal females. Women have used capsules containing . Crit Rev Food Sci Nutr. Boron uses include the ability to improve bone density and prevent bone loss and bone diseases by facilitating calcium, the main mineral involved in bone mineralization, directly into the bones, where it helps prevent porous and weak bones from developing. According to the NIH, the amount of boron in dietary supplements varies between 0.156 mg. Boron is not classified as an essential nutrient for humans because research has not yet identified a clear biological function for boron [2]. Overall, there is a lack of research on the uses of boron, but the potential benefits of boron have been studied, but not proven, for the following: Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, medical doctor, or other healthcare professional. In the largest amount, boron is present in body tissues and fluids as boric acid. You take in boron from foods, but you can also get boron from supplements. Boron may affect levels of calcium and vitamin D, and steroid hormones such as estrogen, which may help to promote bone health. DRI is the general term for a set of reference values used for planning and assessing nutrient intakes of healthy people. 2008 Apr;66(4):183-91. According to 2019 research, a boron-rich diet may result in lowering: Study participants increased their intake of boron through boron-rich foods, such as avocado, dried fruits, and nuts. However, if taken in high quantities while pregnant, boric acid or boron supplements may not be safe for the fetus. In: John W. Erdman Jr. IAM, Steven H. Zeisel, ed. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Benefits Dosage and how to take Side effects Other supplements for arthritis Summary Research suggests that boron may be an effective way to treat the symptoms of rheumatoid arthritis and. Biol Trace Elem Res 1998;66:227-35. about your interest in, questions about, or use of dietary supplements and what may be best for your overall health. However, it should be noted that the study was conducted by researchers funded by the company that manufactures the supplement. Aluminum, boron, calcium, copper, iron, magnesium, manganese, molybdenum, phosphorus, potassium, sodium, and zinc: concentrations in common western foods and estimated daily intakes by infants; toddlers; and male and female adolescents, adults, and seniors in the United States. It has a role in converting vitamin D to its active form, thus increasing calcium uptake and deposition into bone and teeth rather than causing soft tissue to calcify (lose calcium). More research is needed to understand the effects, if any, of boron on cancer. While some people take boron supplements to further boost their intake, its thought that the risk of deficiency is low and that most peoples diets provide enough. It can also help protect bones because of its role in regulating estrogen function. How Does It Work? Can consuming grapes daily increase certain gut bacteria? [, Khaliq H, Juming Z, Ke-Mei P. The Physiological Role of Boron on Health. A scheme training visually impaired women to use their heightened tactile abilities benefits patients and examiners The most satisfying part of Ritika Maurya's work is reassuring the anxious . 1 Boron supplements have several alleged health benefits. Note that the numbers in parentheses (1, 2, etc.) In fact, because levels of boron in foods are highly dependent on how healthy the soil is where the crops are grown, animals that graze on depleted soils low in minerals usually have less muscle and more bone and joint pain as they age than animals raised on boron-rich soils. Fact sheet for consumers. However, evidence for the benefits of boron is either mixed or limited. Jennifer Lefton, MS, RD/N-AP, CNSC, FAND is a Registered Dietitian/Nutritionist and writer with over 20 years of experience in clinical nutrition. Females may lose up to 10% of their bone mass in the 5 years following menopause. The median dietary boron intake in lactating women is 1.27 mg/day [2]. Researchers believe boron works to stabilize molecules within plants, including beneficial polysaccharides and sterols, although the exact way it works in both plants and humans is still somewhat unknown. Baltimore, MD: Lippincott Williams & Wilkins; 2014:248-51. [, Pietrzkowski Z, Phelan MJ, Keller R, Shu C, Argumedo R, Reyes-Izquierdo T. Short-term efficacy of calcium fructoborate on subjects with knee discomfort: a comparative, double-blind, placebo-controlled clinical study. Another clinical trial, including 60 adults with OA, looked at outcomes of boron supplementation. 2015;14(4):35-48. One study showed that elevated levels of boron might be toxic to human development. Biol Trace Elem Res 2019;188:11-25. Effects of dietary boron on cervical cytopathology and on micronucleus frequency in exfoliated buccal cells. Please review this supplement label with your healthcare provider to discuss any potential interactions with foods, other supplements, and medications. Boron. PMID:26770156. [. and can have a rapid effect in helping menopausal women. Children between the ages should not exceed doses of of 17 milligrams per day. Boron is a mineral that is found in food and the environment. There is no recommended dietary allowance (RDA) for boron, but a tolerable upper limit (TUL) was set at 20 milligrams daily. In nature, boron is found in various combinations with other elements/minerals and also oxygen. The type of boron we obtain from food is primarily in the form of boric acid, B(OH)3, which is naturally present only in plants. The role of mineral and trace element supplementation in exercise and athletic performance: A systematic review. According to a 2020 review, supplementing with 3 mg of boron per day may help support bone health and help maintain or prevent loss of bone mineral density. Of course, like with all nutrients, very high levels can also cause potential problems. Boron is known to play a role in extending the half-life of vitamin D and estrogen. In one study, it was found that boron supplements can increase bone formation and inhibit bone resorption, producing therapeutic protection against osteoporosis in animal studies. Join the ODS Email List. Cathy Wong is a nutritionist and wellness expert. Dietary supplements are not regulated in the United States, meaning the Food and Drug Administration (FDA) does not approve products for safety and effectiveness before they are marketed. Ask ODS A double-blind, placebo-controlled pilot study to evaluate the effect of calcium fructoborate on systemic inflammation and dyslipidemia markers for middle-aged people with primary osteoarthritis. Most females experience menopause between the ages of 4555 years. Boron is a trace mineral that has been largely ignored for health maintenance & freedom from disease. However, evidence for the benefits of boron is either mixed or limited. This can be a risk factor for osteoporosis. However, large quantities can be dangerous. In 1985, the US Department of Agriculture (USDA) conducted an experiment in which postmenopausal women (n = 12) who had been put on a low-boron diet (0.25 mg/d for 119 d) were supplemented with 3 mg/d of boron during two 28-day trials. You take in boron from foods, but you can also get boron from supplements. Horses, sheep and other domesticated animals that develop signs of arthritis are sometimes given boron supplements to ease pain and inflammation. You should always consult with a healthcare provider about any new supplements you are considering taking. Estimation of boron intake and its relation with bone mineral density in free-living Korean female subjects. -- You may not have heard about boron, or how it may benefit your health. The Importance of Boron Nutrition for Brain and Psychological Function. Bone Growth and Maintenance. Therefore, information on boron levels in foods is limited. While a comprehensive list of boron content within common foods isnt yet available, below are believed to be the highest food sources of boron: Another fun fact about boron uses? Summary During menopause and postmenopause, bone density decreases. However, PSA levels did not differ significantly between the two groups. While theres still a lot to learn about this mineral, one of the most researched boron uses is its ability to increase estrogen levels in both healthy women and men, which is one reason its linked to healthy bones and fewer signs of age-related diseases like cognitive decline and arthritis. Iavazzo C, Gkegkes ID, Zarkada IM, Falagas ME. Boron may affect calcium, vitamin D, and estrogen levels, which all play a part in bone health for menopausal or postmenopausal females. Boron is a trace element occurring in many plant foods. In some individuals, oral consumption of boron was found to reduce these symptoms if the supplement is taken each day of the menstrual cycle. It is considered a nonessential nutrient for humans. During menopause and postmenopause, bone density decreases. Sex drive may return within just a . Let us acquaint you with the various boron benefits and also give you an insight into some common side effects of boron in this article. Always speak with a healthcare provider before taking a supplement to ensure that the supplement and dosage are appropriate for your individual needs. No data are available on adverse effects of high boron intakes from food or water [2]. J Trace Elem Med Biol 2018;45:156-62. It is beneficial to both men and women as women usually use boron in the form of boric acid to treat conditions like vaginal yeast infection. [, Rainey CJ, Nyquist LA, Christensen RE, Strong PL, Culver BD, Coughlin JR. Daily boron intake from the American diet. Biol Trace Elem Res 2017;176:278-93. Boron is a trace element that is present in many plant foods. During this time, periods stop, and estrogen levels decline, leading to a loss of bone density. . Boron is likely safe to take if used in appropriate amounts. While 71% of employers have a positive perception of the company's culture toward menopause, only 32% of women employees agree. Not only does boron help to regulate estrogen, but it also helps to balance all the sex hormones. Most studies suggest that urinary boron levels correlate with boron intakes [2,4,16,17]. Side Effects Precautions Dosage Boron is a naturally occurring element found in plant foods. We encourage you to talk to your health care providers (doctor, registered dietitian, pharmacist, etc.) Most Americans consume 13 milligrams of boron daily through their diet alone. Scientifically reviewed by: Dr. Gary Gonzalez, MD, in January 2021. The total intake of boron from food and supplements ranges from 1 to 1.5 milligrams daily. However, boron supplements may increase the amount of magnesium that stays in your body, increasing blood levels of magnesium. This article looks at boron, which foods contain it, the potential benefits of boron, and its side effects. People may experience: Below are answers to some common questions about boron. Boron status (measured in urine or blood) is not routinely checked. There is no evidence that modest consumption of boron through diet and supplements affects hair loss. This can prevent arthritic pain and discomfort and prevent the worsening of arthritis. Penland JG. Using lubricants can help prevent irritation or pain. Most ingested boron is hydrolyzed to boric acid within the gastrointestinal tract [6]. Fasting plasma concentrations of boron in postmenopausal women range from 34 to 95 ng/mL (3.14 to 8.79 mcmol/L) [4]. Boron is found in many plant-based foods, including: Boron supplements come in many different forms, such as: There is no evidence to support using one form over the other. We avoid using tertiary references. Osteocalcin is a protein found in bones and teeth. Summary. Faseb j 1987;1:394-7. Biol Trace Elem Res 2018;186:31-51. The FNB established boron ULs for healthy individuals based on levels associated with reproductive and developmental effects in animals [2]. [, Litovitz TL, Klein-Schwartz W, Oderda GM, Schmitz BF. Menopause can cause vaginal dryness. Boron toxicity is not common when consuming whole foods, but taking high doses of supplements can potentially become dangerous and cause negative reactions. How do you get boron in your diet? . J Trace Elem Med Biol 2012;26:157-60. Everything You Need to Know About Vitamin K, 10 of the Highest Boron Foods for Healthy Bones and More, Supplements for Joint Pain: 10 Effective Options, The 5 Best Natural Sleep Aids of 2023, According to a Dietitian, The 9 Best Vitamin D Supplements, According to a Dietitian. Extremely high doses of boron can be fatal; for example, 15,000 to 20,000 mg can cause death in adults [6,9]. However, there has been little recent research into its effects. [, Armstrong TA, Spears JW, Crenshaw TD, Nielsen FH. Boron is an active ingredient in tablets used totreat yeast infections in women. Note that the numbers in parentheses (1, 2, etc.) Youll find it in many whole foods, especially. If the trace mineral is not in the soil, then it's not going to be in the plants. One study indicated that taking at least three milligrams per day of boron may have anti-inflammatory effects, which can help with osteoarthritis. Fruit cocktail, canned, in heavy syrup, cup, French fries, from frozen, deep fried, 10 fries. Is Boron good for muscles and hair? Thank you, {{form.email}}, for signing up. Am J Emerg Med 1988;6:209-13. The body absorbs about 85%90% of ingested boron [2,4]. Is boron harmful to humans? It is also shown to positively impact the body's usage of testosterone, estrogen, and vitamin D. However, more research is needed. The NIH reports that boron may play an important role in bone growth and formation. However, even if supplements are third-party tested, that doesn't mean they are necessarily safe for all or effective in general. Debra Sullivan, Ph.D., MSN, R.N., CNE, COI, Causes and treatment for menopause fatigue, 3 Best Lubricants for Menopause Dryness 2023: Water, Silicone, Oil, and More, increase calcium and magnesium excretion in urine. Very high doses of boron can be toxic, and doses of 15,00020,000 mg can be fatal in adults. Additional research is needed to determine whether boron supplementation affects bone health in humans. According to the National Institutes of Health (NIH), plants require boron for growth and pollination, but experts do not deem it essential for human health. In fact, some farmers even treat soil with high levels of boron and give boron supplements to their livestock to reduce the effects of radiation in the environment. Children and teens need between 6 and 17 milligrams/day, while adults need about 20 milligrams/day. The amount of this mineral that children and adults need depends on their age. Signs and symptoms of a boron deficiency have yet to be established, making it hard to know who may be at risk of a deficiency. When you visit the site, Dotdash Meredith and its partners may store or retrieve information on your browser, mostly in the form of cookies. What is boron used for? Boron supplementation improves bone health of non-obese diabetic mice. Boron in the diet or taken as a supplement may benefit bone health. Learn more about menopause fatigue. In animal studies, boron depletion is linked with fertility problems and birth defects, which suggests that boron can play a role in healthy reproduction and fetus development. It helps diminish bacteria growth, and its a natural way to prevent crops from spoiling. Although there is no recommended daily intake of boron, the upper limit is 20 mg per day for adults aged 19 or over, including pregnant and lactating females. The lowest active dose that has beneficial effects seems to be about three milligrams/day for adults. [. Symptoms associated with accidental consumption of boric acid or borax (sodium borate), contained in some household cleaning products and pesticides, include nausea, gastrointestinal discomfort, vomiting, diarrhea, skin flushing, rash, excitation, convulsions, depression, and vascular collapse [2,6,46]. Too much thyroid hormone can cause bone loss. Boron may be suitable for arthritis when taken in appropriate amounts. 2023 Healthline Media UK Ltd, Brighton, UK. It has anti-cancer effects as well. Activation of the EIF2alpha/ATF4 and ATF6 Pathways in DU-145 Cells by Boric Acid at the Concentration Reported in Men at the US Mean Boron Intake. Bentham Science Publishers doi: 10.2174/1573407215666190308152952, Iavazzo C, Gkegkes ID, Zarkada IM, Falagas ME. Certain vitamins and minerals are better absorbed and utilized by the body when boron levels are higher, which is important for building muscle,burning fatand preventing pain by recovering muscle-tissue tears following exercise. People can also take boron as a supplement. Boron citrate has gained so much traction for its positive impact on your body's production of testosterone. Recommended Dietary Allowance (RDA): Average daily level of intake sufficient to meet the nutrient requirements of nearly all (97%98%) healthy individuals; often used to plan nutritionally adequate diets for individuals. In a small human study, boron as sodium tetraborate significantly increased plasma boron levels within 46 hours of consumption [5], but no data are available on the relative bioavailability of different forms of supplemental boron. If you or someone you know overdoses on boron, seek medical help or call the Poison Control Center. Biol Trace Elem Res 1998;66:193-204. Another advantage of taking boron is it's ability to strengthen bones and delay the onset of osteoporosis, which is another side effect of low oestrogen levels. There is some evidence that dietary boron intake might reduce the risk of certain cancers, such as prostate cancer and lung and cervical cancer risk in women. According to data from the Third National Health and Nutrition Examination Survey (NHANES III; 1988-1994) and the Continuing Survey of Food Intakes by Individuals (19941996), median dietary boron intakes range from 0.87 to 1.35 mg/day in adults, 1.05 to 1.08 mg/day in pregnant women, and 0.75 to 0.96 mg/day in school-aged children [2]. Updated: Melissa Nieves, LND, RD, is a registered dietitian working for a private practice. Is it possible to have both great hair and big muscles.. Boron produced no unwanted side effects and was also self-made and much less expensive than the cream, leading researchers to conclude that boric acid is a natural fungistatic and can be a better, cost-effective option than messy vaginal creams. This article will use the terms male, female, or both to refer to sex assigned at birth. The half-life is the . The daily upper limits for boron boron include intakes from all sourcesfood, beverages, and supplementsand are listed below in milligrams (mg). It is a structural component of plant cell walls and is required for plant growth, pollination, and seed formation [1]. However, no human studies have proven that boron can impact bone density. Determining human dietary requirements for boron. Boron Health Benefits 1) Bone Strength. Nielsen FH, Eckhert CD. This article will review what boron is, its possible benefits, and what is known about dosage and risks. [, Newnham RE. (This includes pregnant or breastfeeding women over 19 years of age.). Osteoarthritis Am J Epidemiol 2008;167:1070-80. National Institutes of Health. As for all supplements, look for ones that have been third-party tested, as minerals may have toxic heavy metals found in them (e.g., lead and arsenic). These organizations include U.S. Pharmacopeia, ConsumerLab.com, and NSF International. Boron also has anti-inflammatory effects that can . Areas of the world with limited boron in the soil include Brazil, Japan, and most of the United States, mainly because of high levels of rainfall, which leaches boron out of the soil [21]. There is little research to support further supplementation with boron. It also helps protect against bone weakness and conditions like osteoporosis because it regulates the function of estrogen in both women and men. In: Coates PM BJ, Blackman MR, Cragg GM, Levine M, Moss J, White JD, ed. Biol Trace Elem Res 2008;125:213-22. Overview Boron is an element. No supplement is intended to treat, cure, or prevent a disease. When ingested, boron is converted to boric acid and absorbed in the gastrointestinal tract; the body absorbs about 85% to 90% of ingested boron. These values, which vary by age and sex, include: The FNB found the existing data insufficient to derive an RDA, AI, or EAR for boron [2]. Investigating the power of music for dementia. [1] Aids in Wound Healing As a mineral that can help balance levels of sex hormones in both women and men, including estrogen and testosterone, boron helps relieve menopause symptoms as well as PMS, and also for increasing fertility. Boron seems to affect the way. Improves cognitive function in the elderly. Update on human health effects of boron. Estimated Average Requirement (EAR): Average daily level of intake estimated to meet the requirements of 50% of healthy individuals; usually used to assess the nutrient intakes of groups of people and to plan nutritionally adequate diets for them; can also be used to assess the nutrient intakes of individuals. It's important to note that self-treating a condition and avoiding or delaying standard care may have serious consequences. [, Hunt CD, Shuler TR, Mullen LM. [. New research reveals a system-wide benefit that includes shrinking prostate tumor volume, lowering PSA levels and reducing prostate cancer risk. According to the preliminary results, short-term calcium fructoborate supplementation reduced markers of inflammation (e.g., C-reactive protein). Men and women both can avail boron health benefits for different health issues like diabetes, hormonal imbalance, osteoporosis, osteoarthritis, inflammation, and so on. Can diet help improve depression symptoms? 2011;144(1-3):253-263. doi:10.1007/s12011-011-9083-0, Reyes-Izquierdo T, Argumedo R, Phelan M, et al. Some of its benefits include the following: Relieves Menstrual Pain According to MedlinePlus, it may help reduce the severity of menstrual pain. There are no known medication interactions with boron. You can find out more about our use, change your default settings, and withdraw your consent at any time with effect for the future by visiting Cookies Settings, which can also be found in the footer of the site. If you're considering taking boron, make sure to consult your healthcare provider first. The federal government's 2020-2025 Dietary Guidelines for Americans notes that "Because foods provide an array of nutrients and other components that have benefits for health, nutritional needs should be met primarily through foods. In addition, a low-boron diet (0.25 mg boron/2,000 kcal) might elevate urinary calcium and magnesium excretion and lower serum concentrations of estrogen in postmenopausal women [8,29]. Mechanisms of action of potent boron-containing antifungals, Boric acid for recurrent vulvovaginal candidiasis: The clinical evidence, The role of mineral and trace element supplementation in exercise and athletic performance: A systematic review, Boron exposure through drinking water during pregnancy and birth size, Treatment of vaginitis caused by Candida glabrata: use of topical boric acid and flucytosine. 2019, 11(3), 696. doi:10.3390/nu11030696, Malin Igra A, Harari F, Lu Y, Casimiro E, Vahter M. Boron exposure through drinking water during pregnancy and birth size. Hunt C. Boron. If people are unsure about taking boron supplements, they can discuss with a healthcare professional. Plant foodsincluding fruit, tubers, and legumescontain the largest amounts of boron [2,6,15,18,19]. From boosting free testosterone levels to blocking excess estrogen (and preventing man boobs); Boron can also be used to increase muscle and bone strength; improve mental clarity, focus, and concertation; develop muscle coordination, decrease inflammation and assist arthritis. [, Kobylewski SE, Henderson KA, Yamada KE, Eckhert CD. Increasing boron intake may help slow down the loss of bone density during menopause, although there is a lack of recent research to support this. [, Dessordi R, Spirlandeli AL, Zamarioli A, Volpon JB, Navarro AM. Boron might be important for bone growth and formation, possibly by affecting osteoblast and/or osteoclast activity or by influencing serum steroid hormone levels and calcium metabolism [4,6,11,32]. Women also use boron specific to their needs; in capsule form, boron contains boric acid, which has been found useful for treating yeast infections inside the vagina, per webmd.com. It is essential to consult with a healthcare provider before starting any supplements. When possible, choose a supplement that has been tested by a trusted third party, such as USP, ConsumerLabs, or NSF. When rats were fed a boron-deprived diet, they experienced spongy bones, bone loss in the femurs and lumbar vertebrae, and increased osteoporotic conditions. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Boron supplementation of a semipurified diet for weanling pigs improves feed efficiency and bone strength characteristics and alters plasma lipid metabolites. On the other hand, rats given high-boron supplements showed improvements in bone mass, bone thickness, bone volume and higher levels of estradiol (a hormone tied to bone health). Regul Toxicol Pharmacol 1995;22:221-30. [, Nielsen FH, Hunt CD, Mullen LM, Hunt JR. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. Essentiality of boron for healthy bones and joints. Other research shows that animals and humans who ate a diet with boron supplementation had improved bone density. Low boron levels may link to an increased risk of osteoporosis, while diets higher in boron may help improve bone density. [, Scorei IR. Boron is a safe and workable alternative when inserted into the vagina to speed up the healing process of painful infections. Boron uses include acting as an astringent tohelp prevent or treat infections on the skin, so its useful for lowering redness, inflammation, pain and other signs of irritation. Comparisons of animals receiving boron supplementation with animals that consume usual or small amounts of boron show that the supplementation improves some measures of bone strength [36-38]. A deficiency in boron is rare. A vital trace mineral that is found in foods and the environment, people may also take boron as a supplement. Environment International. By Jennifer Lefton, MS, RD/N, CNSC, FAND In men, low testosterone levels can cause a loss of bone mass. And because boron helps to promote . The maximum tolerable intake is between one to 20 milligrams per day for adults, which means you should not exceed this amount (unless working closely with a doctor). J Am Diet Assoc 1999;99:335-40. In two small studies by the U.S. Department of Agriculture, when menopausal womenwere first fed a diet that provided low levels of boron and then were fed a diet richer in boron, they experienced lower levels of calcium and magnesium loss through urine and elevated (but still considered healthy) levels of estrogen and testosterone. More research is needed to determine if boron indeed has any effect on cancer. Additionally, studies show it can help the body produce and use vitamin Dbetter, which is a crucial nutrient for healthy bone formation, in addition to many other things likeimmune function and cognitive processes. Excessive intake of boron can be dangerous to health. Total blood boron concentrations range from 15.3 to 79.5 ng/g. However, this study was very small and not blinded or placebo-controlled. Boron helps in improving levels of estrogen found in postmenopausal women, thus decreases symptoms derived from menopause such as mood swings and hot flashes. Boron is a trace mineral that may help with bone health and benefit you in other ways. Results showed improvements in task performance on various cognitive and psychomotor tests in the group receiving more, including better response times, motor skills and manual dexterity, eye-hand coordination, attention, perception, and both short- and long-term memory. However, it might have beneficial effects on such functions as reproduction and development, calcium metabolism, bone formation, brain function, insulin and energy substrate metabolism, immunity, and the function of steroid hormones (including vitamin D and estrogen) [ 1-14 ]. The Benefits of Using Boron Citrate. In a placebo-controlled clinical trial of 17 female athletes (mean age 19.8 years) and 11 sedentary females (mean age 20.3 years), 3 mg/day boron supplementation for 10 months significantly reduced serum phosphorus levels and increased serum magnesium levels in sedentary females; such changes are often associated with increased bone mineral density [40]. Vegetarians tend to have a higher intake. Boric acid for recurrent vulvovaginal candidiasis: The clinical evidence. Additionally, this mineral is linked to improved brain function in some instances, since it can help boost concentration, focus and the ability to learn new information. Journal of Women's Health. doi:10.1067/s0002-9378(03)00726-9. According to the NIH, plant foods such as fruit, tubers, and legumes, are highest in boron. The amount of boron in plant foods depends somewhat on the boron content of the soil and water where they were grown [7,21]. Among toddlers, 38% of boron intakes comes from fruits and fruit juices and 19% from milk and cheese [6,20]. Institute of Medicine. According to a 2018 article published in World Journal of Translational Medicine, Nowadays, there is a boom in research on new BCCs as potential tools in the prevention, diagnosis and therapy of human disease.. Various organs have various levels of boron. Prolonged absence of menstruation (amenorrhea) before menopause also increases the risk of osteoporosis. Observational evidence combined with the findings from a few small clinical studies in humans suggests that boron might be helpful for reducing the symptoms of osteoarthritis, possibly by inhibiting inflammation [3,30-33]. Improved estrogen balance may help relieve menopause symptoms as well as PMS. Industrial uses also include its ability to capture radioactivity within soils, ionizing it and reducing potential health risks like cancer. Bone health Boron has not been studied in breastfeeding women, therefore, it is not recommended for use while nursing. Additionally, there is no RDA set for boron. National Institutes of Health. The bones, nails, and hair have higher boron levels than other body tissues, while fat has lower levels Boron is excreted mainly in the urine, but small amounts are excreted in the feces, sweat, and breath. Although experts do not currently consider boron essential for human health, it may have health benefits for females going through menopause and postmenopause. Nothing boring about boron. Benefits from obtaining enough boron from your diet (sometimes with help from supplements) include support for bone health, healthy hormone production, brain/cognitive functions, prevention of arthritis and immune support. If people consume excessive amounts of boron, it can cause toxicity. Boric acid is the main form of boron in blood, urine, and other body fluids [2,4,7]. Calcium Fructoborate: Plant-Based Dietary Boron for Human Nutrition. For more information about building a healthy dietary pattern, refer to the Dietary Guidelines for Americans and the U.S. Department of Agriculture's MyPlate. Manganese, Molybdenum, Boron, Chromium, and Other Trace Elements. Boron has been consumed for menstrual cramps and boric acid has been used vaginally for yeast infections, but evidence is limited. However, some research suggests that it may benefit osteoarthritis and yeast infections. . Boron does not accumulate in most body tissues, but bone, nails, and hair have higher boron levels than other body tissues, whereas fat has lower levels [9]. In women, bone loss increases dramatically at menopause due to dropping estrogen levels. 1. According to a 2015 review of boron literature published in IMCJ, taking a 6-mg dose of boron for just a week has the following benefits: increases the metabolism of the total testosterone. Based on research findings, most people seem to get the majority of their boron from foods like coffee, milk, apples, beans and potatoes. Moreover, this reduces the dangers of fungal infections like candida albicans. According to results from a double-blind comparison study looking at the effects of boron compared to another type of commercial yeast infection cream (made from nystatin), boron was better able to treat yeast infections. Additionally, boron is found mainly in plant foods, and consuming more fruits and vegetables is generally recommended for reducing cancer risk. The National Institutes of Health (NIH) cautions that boron supplements or high dietary intake of boron may be harmful to people with hormone-sensitive conditions, including breast cancer, endometriosis, and uterine fibroids. 12 Health Benefits of Zinc for Women, According to Nutrition Experts. Nielsen FH. Boron is a naturally occurring element found in plant foods. Low boron intakes (0.23 mg boron/2,000 kcal) also appear to reduce plasma calcium and serum 25-hydroxy vitamin D levels and raise serum calcitonin and osteocalcin levels in men and women [8]; these changes could affect bone mineral density. Cleaning products and pesticides containing boric acid or sodium borate can be harmful if someone accidentally consumes them. Boron acts as a natural food preservative within foods. Wine, cider, and beer also contain boron [8]. Sex and gender exist on spectrums. Fundam Appl Toxicol 1997;35:205-15. Boron plays an important role in the integration of calcium into the joints cartilage, which helps prevent joint deterioration andarthritis pain. Boron and fish oil have different beneficial effects on strength and trabecular microarchitecture of bone. Fact sheet for health professionals. Prevents inflammation Boron is a potent anti-inflammatory that plays an essential role in integrating calcium into the bones, including the joint cartilage. It can increase testosterone levels and estrogen in postmenopausal women. J Trace Elem Med Biol 2017;39:169-75. Boric acid is just one form of this mineral and one of dozens of boron containing compounds (BCCs) found in nature and available from chemical synthesis. Biol Trace Elem Res 1998;66:65-78. 1. Learn about the best lubricant for menopause dryness here. Therefore, the benefit cannot be confirmed. Most healthy people are likely getting adequate boron through their diet alone, so supplementation may not be necessary. The Dietary Guidelines for Americans describes a healthy dietary pattern as one that: This fact sheet by the National Institutes of Health (NIH) Office of Dietary Supplements (ODS) provides information that should not take the place of medical advice. J Dairy Sci 1992;75:3050-5. One 2019 systematic review of mineral and trace element supplementation in athletes suggested that seven weeks of boron supplementation had no effect on athletic performance. [, Muezzinoglu T, Korkmaz M, Nese N, Bakirdere S, Arslan Y, Ataman OY, et al. No clinical trials have evaluated the effects of boron on cancer prevention or treatment. Ninety-two percent of women had relief after seven to 10 days of treatment compared to 64 percent using the standard cream. Can diet and exercise reverse prediabetes? Boron is thought to help prevent a range of conditions, including: This mineral can even help animals suffering from pain. If you have a history of estrogen-sensitive cancer or are on hormonal therapy, avoid taking high amounts of boron. Other study observations show evidence that bones of patients using boron supplements are much harder to cut than those of patients not using supplements. The upper limit of intake for children varies by age, as follows: Although the few clinical trials published used a boron dose ranging from 1 milligram to 6 milligrams daily, it is generally believed to be safe between 1 and 20 milligrams daily. Includes a variety of vegetables; fruits; grains (at least half whole grains); fat-free and low-fat milk, yogurt, and cheese; and oils. [, Chapin RE, Ku WW, Kenney MA, McCoy H, Gladen B, Wine RN, et al. In addition, boron is eliminated primarily through the kidneys, so it should be avoided by people with kidney disease or problems with kidney function. Biol Trace Elem Res 2019;188:2-10. It's also a source of taurine, citrulline, and phenylalanine . A subsequent double-blind, placebo-controlled trial examined the effects of 1.5, 3, or 6 mg/day boron (as calcium fructoborate) for 2 weeks on inflammatory biomarkers (e.g., C-reactive protein and fibrinogen) in 60 participants with osteoarthritis aged 5968 years [30]. All rights reserved. However, in an observational study in 134 Korean women (average age 41 years), boron intakes (mean of 0.9 mg/day) were not significantly correlated with bone mineral density in the lumbar spine or femoral regions [39]. Its widely recognized as being very safe for consumption in both humans and animals. By Alyssa Jung Published: May 30, 2023. The NIH classes a low boron intake as 0.230.25 milligrams (mg) boron per 2,000 calories (kcal). Water contains boron, but the concentration varies considerably by source [19]. In contrast, arid regions of the worldincluding California and parts of Turkey, Argentina, Chile, Russia, China, and Peruhave higher boron concentrations [21,22]. However, very little is known about how or where in the gastrointestinal tract absorption occurs [8]. The World Health Organization (WHO) recommends that an "acceptable safe range" of boron intake ranges from 1 to 13 milligrams daily. [, Meacham SL, Hunt CD. Boron in the diet or taken as a supplement may benefit bone health. The NIH states that blood boron levels tend to remain constant even when a person greatly increases their dietary intake of boron. In very high doses, boron may lead to alopecia in adults and cause thin hair in infants. The median boron concentration of drinking water in the United States is 0.031 mg/L [24]. Protects against damage wrought by pesticide exposure and heavy metal accumulation. Boron is thought to be useful for building strong bones and muscles, treating osteoarthritis, increasing levels of testosterone in the blood, and improving cognitive skills and muscle coordination. Improved wound healing. Boric acid is a combination of boron, oxygen and hydrogen. Selected food sources of boron are listed in Table 1. Scorei R, Mitrut P, Petrisor I, Scorei I. A boron supplement of 3 mg/day marked [, Korkmaz M, Uzgoren E, Bakirdere S, Aydin F, Ataman OY. One theory is that this mineral has anti-inflammatory effects, antioxidant-like capabilities, and that it assists the body in handling other minerals like magnesium, calcium, sodium and phosphorusby producing necessary digestive enzymes. [, Hunt CD. Pflugers Arch 2008;456:671-7. Preliminary evidence suggests that dietary boron intake might affect cancer risk. J Trace Elem Med Biol 2014;28:383-7. 2016;95:54-60. doi:10.1016/j.envint.2016.07.017, Pizzorno L. Nothing boring about boron. Boron can be safe when used as recommended. Environ Toxicol 2007;22:17-25. Her experience ranges from counseling cardiac rehabilitation clients to managing the nutrition needs of complex surgical patients. In a two-part study, researchers gave 12 postmenopausal women a diet providing 0.25 mg of boron for 119 days. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. Nielsen FH. Do not insert boric acid to the vagina in the first four months of pregnancy, however, as it can potentially cause birth defects. Benefits. Encyclopedia of Dietery Supplements. These findings suggest that boron, particularly as calcium fructoborate, might hold promise for reducing osteoarthritis symptoms, but confirmation is needed from additional controlled trials. It is known to balance certain hormones such as estrogen and testosterone. Uluisik I, Karakaya HC, Koc A. Taking 20 milligrams of boron daily is considered a very high dose, and most studies suggest its best to start with a lower dose around three to six milligrams daily. are clickable links to these studies. Jennifer Lefton, MS, RD/N-AP, CNSC, FAND is a Registered Dietitian/Nutritionist and writer with over 20 year of experience in clinical nutrition. Cancer The Fructoborates: Part of a Family of Naturally Occurring Sugar-Borate Complexes-Biochemistry, Physiology, and Impact on Human Health: a Review. In some cases, fortified foods and dietary supplements are useful when it is not possible otherwise to meet needs for one or more nutrients (e.g., during specific life stages such as pregnancy).". Its a mineral that we obtain from a variety of foods, mostly plants, and also in small amounts from drinking water. 2003 May;58(5):351-8. Carbohydrates: 11.5 g. Fiber: 0.6 g. Sugar: 9.4 g. Vitamin C: 12.5 mg: 14% DV. 2003;43(2):219-31. Boron contributes to everything from hormone levels to brain function. Depression is more common during menopause, but it is unclear if menopause directly causes it. Read our. In a small pilot study that compared 6 mg boron per day for 8 weeks with placebo, the supplements reduced symptoms of osteoarthritis in 20 participants younger than 75 years (mean age about 65 years) [33]. To be safe, do not take high doses without working with a doctor. Research shows people with lower boron concentrations in their bones and synovial fluid experience higher rates of arthritis than those with higher levels. It is sometimes said to help with recurrent vaginal yeast infections when used as a vaginal suppository. Integr Med (Encinitas). Another health benefit from boron would include the maintenance of a strong . Tolerable Upper Intake Level (UL): Maximum daily intake unlikely to cause adverse health effects. Good news! Boron is an important, and often underutilized, trace mineral naturally present in certain foods and also within the environment. Theupper limit for boron depends on your age and gender and are as follows: This means that the tolerable upper intake level of boron, the the maximum dose at which no harmful effects would be expected, for adults is 20 milligrams per day. Boron can also be bound to calcium, sodium and lithium. Similarly, its used by many athletes and bodybuilders because its believed to increase the bodys ability to produce and use testosterone, so its beneficial for recovering from exercise, preventing aches and pains, building muscle mass, and keeping bones strong. People can also take boron as a supplement. How Does Boron Deficiency Happen? However, this association has not been evaluated in clinical trials. The World Health Organization estimates that an acceptable safe range of boron intakes for adults is 113 mg/day [8]. [, Cui Y, Winton MI, Zhang ZF, Rainey C, Marshall J, De Kernion JB, et al. In: A. Catharine Ross BC, Robert J. Cousins, Katherine L. Tucker, Thomas R. Ziegler, ed. Therefore, other factors may have also played a part in weight loss, such as an increase in: Boron supplementation of 3 mg per day may benefit bone health and bone mineral density. 2014; 9:895-9. doi:10.2147/CIA.S64590, Arvanitis C, Rook, T. Macreadie I. Mechanisms of action of potent boron-containing antifungals. As a mineral that can help balance levels of sex hormones in both women and men, including estrogen and testosterone, boron may aid in relieving menopause symptoms as well as PMS. In another double-blind, placebo-controlled clinical trial, supplementation with 6 mg/day boron (as calcium fructoborate) for 2 weeks significantly reduced knee discomfort in 60 adults (mean age 50 years) with self-reported knee discomfort [34]. 4. 10th ed: Wiley-Blackwell; 2012:586-607. For example, in a case control study of 763 women with lung cancer and 838 healthy women, those in the lowest quartile of boron intake (less than 0.78 mg/day) had almost twice the risk of lung cancer of those in the highest quartile (more than 1.25 mg/day) [44]. While side effects are not very common, they can include: As always, its best to get this mineral (and all other vitamins and minerals) from real whole foods whenever possible, as opposed to supplements. Boron in certain forms can be dangerous. SuperAger and Alzheimer's brains share similar pathologies, so what sets SuperAgers apart? However, it might have beneficial effects on such functions as reproduction and development, calcium metabolism, bone formation, brain function, insulin and energy substrate metabolism, immunity, and the function of steroid hormones (including vitamin D and estrogen) [1-14]. Boron can aid in keeping your bones strong along with possibly improving brain function. It may help support fertility as well. Boric acid is a form of boron. [, Yamada KE, Eckhert CD. Environ Health Perspect 1994;102 Suppl 7:79-82. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. , Pizzorno L. Nothing boring about boron, and its side effects Precautions boron... Products and pesticides containing boric acid or boron supplements are much harder to cut than boron benefits female with higher.. Plant-Based dietary boron as a vaginal suppository including: this mineral are thought to be safe, do take! 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