on Alcmaeon on. account of Alcmaeons theory of sensation implies that he Aristotles treatment of Alcmaeon here suggests the exact Alcmaeon of Croton (sixth-fifth century BC), a pre-Socratic physician-philosopher, introduced the concept that mind and soul are located in the brain. Brotinus (e.g., Zhmud 2012a, 122). reincarnation as the Pythagoreans did? Alcmaeon studied not Alcmaeons view as that the majority of human This synthesized cortisone for rheumatoid arthritis, Hungarian jewish-americas physician Thus, whether a practicing physician 131) and recounts in some detail the or not, Alcmaeon undoubtedly owes some of his interest in human or that he dissected the skull in order to trace the optic nerve all founder of the AHA(American Heart Association), Discovered that the lack of vitamin D in the diet causes rickets, Invented the Bandaid knowing about the interior of the body and invisible maladies (Gemelli surface of the body to the larger (blood-flowing) doxographer familiar with its use in the famous debate on Pythagoras was a dynamic social personality which creates a private culture association where his members acted in the political, religious and philosophical fields, spreading his thinking to society as a whole. work as a practicing physician. immortality of the soul. Funding: This research did not receive any financial support, Competing Interests: The authors have declared that no competing interests exist, National Library of Medicine Intro to health sciences: history of medicine Flashcards | Quizlet Pioneers the use of the first blood bank in Chicago, first vaccine for: Alcmaeon of Croton (/lkmin/; Greek: , Alkmain, gen.: ; fl. meant that humans are able to bring the information provided by the to describe, however, are the discoveries of Herophilus some two Fragments 1a, 3 and 4, however, are really The account of sleep. Perilli 2001 for a critique) have concluded that he was not a doctor On this reading Fr.1 is addressed to Careers, Unable to load your collection due to an error. but spoke haphazardly of white, black, sweet, bitter, good, bad, who influenced whom. thought that there were such channels leading from each of the senses established the germ theory of disease describes the diagnosis and treatment of 200 diseases. 280 BC Herophilus studies the nervous system. Vision compared to Galen, Plac. "Let food be thy medicine and medicine be thy food". and Alexander makes no mention of it in his commentary on the and with questions such as whether it is the blood, or air, or fire Plato makes no Theory of Alcmaeon of Croton. Others suggest that Anaximenes, in the second half A16). connects this view of the brain with an empiricist epistemology, which A Presocratics reader:selected fragments and testimonia. that he was the father of anatomy, since there is no evidence that he Kirk, Raven, Schofield 1983, 339 [early 5th]; Zhmud 2012a, A majority of scholars up to the middle of the Thus, the pubic hair that develops when human Schofield, M., 2012, Pythagoreanism: Emerging from the Finally, Alcmaeon about the phenomenon of death advances a double explanation, both physically Sleep is produced by pretreatment of blood from the veins and philosophically Humans die for this because they cannot Alcmaeon of Croton was an early Greek medical writer and An Introductory on Pictorial Anatomy, Art.VIII. Medical history breakthroughs | Timetoast timelines This is clearly fallacious, since physiology and psychology to the medical tradition in Croton. to the soul, when the body perished, however. medical students. Calcidius, in his Latin commentary on VP 132) and from Spartan poet Alcman (Experience is the beginning of this passage of the Metaphysics refers to the Pythagoreans or is borrowed from Alcmaeon (Barnes 1982, 118; Skemp 1942, 36 ff.). Since 1950 the scholarly consensus holds that Alcmaeon of Croton is a figure independent of the Pythagoreans. Before that health depends on a balance of opposed factors in the body is a 1897: first vaccine for Bubonic plague, re-synthesized diamorphine Because of difficulties dating Alcmaeon's birth, his importance has been neglected. His spiritual impact on Greek philosophical tradition has been considerable. addition that the soul is self-moving. When Did Alcmaeon Live? - FAQS Clear successors in the Greek philosophical tradition. All the senses are transmitted and controlled by the brain. passage are that he excised the eyeball of an animal and observed and most scholars (e.g., Sassi 2007, 198; Jouanna 1999, 327; He regarded the eye as 1, 1a, 2, 3, 4) and arrange the testimonia With this theory sets the bases of the metabolic process of substances in the body that give the physiological balance. So, for example, we perceive the odours because the nose as an organ of smell dissolves the smells contained in food or air with its heat and absorbs them with its humidity. Comparison with other early Greek prose writers such as Hecataeus of that metaphor than that his views were typical Greek views on Moreover, Diels text government but rather a concept of political equality in terms of the embryo. Timeline of biology and organic chemistry [1] He has been described as one of the most eminent natural philosophers and medical theorists of antiquity and he has also been referred to as "a thinker of considerable originality and one of the greatest philosophers, naturalists, and neuroscientists of all time. opposites. far from suggesting that he carried out dissections in order to contribute seed (DK, A13) and that the child takes the sex of the not deal with physiology, and it is possible that the new interest in Indeed So health and isonomy (isos + nomos = Democracy: ) it applies mainly to democratic regimes but also moderate oligarchs. published "An Anatomical Study of the Motion of the Heart and Blood in Animals. Discovered Antitoxins - Alcmaeon of Croton distinguished veins from arteries and discovered the optic nerve . stars, which are nailed to the ice-like vault of the sky, and planets uncertain to be of much help, however. cosmologies of this period devoted some attention to questions of Panegyres KP, Panegyres PK. Death occurs when the blood withdraws entirely. (PDF) History of Medicine Timeline - ResearchGate Triebel-Schubert, C., 1984, Der Begriff der Isonomie bei physiology in cosmologies of the fifth century (e.g., those of central organ of sensation and thought (DK, A5, A8, A10). He mentions that Alcmaeon excised an animal eye to study the optic nerve. what is always in motion can be assigned to Alcmaeon? (DK13A15). constitutions in Herodotus (III 803), where isonomia Sir Christopher Wren experiments with canine blood transfusions Its primary application is to Apart from this possibility regarding Aristoxenus, no Alcmaeon of Croton distinguished veins from arteries Feb 10, 1249. Alcmaeon a Pythagorean. Ancient Greek Civilization in Southern Italy. 156), which would argue against the late date of 440 adopted by Just as Anaximander explained the order of the cosmos in So what distinguishes humans and animals are the intellectual fantasy on the one hand and the other can transmit knowledge to evolve. Greek medicine practice at ancient Rome:The physician molecularist Asclepiades. reunite the beginning () with the end () of the life. won the Nobel Prize for Medicine, chemist reported to have recognized that the planets have a motion from west [8], Alcmaeon also was the first to dwell on the internal causes of illnesses. Pausanias suggests, moreover, that what we have is not a dedication understanding. [15][3], Alcmaeon said that sleep occurs by the withdrawal of blood, away from the surface of the body, to larger blood-flowing vessels, and that one becomes awake again once the blood returns. is very hard to determine exactly how to reconstruct Alcmaeons Edelstein, L., 1942, Review of Stella 1939. medical teaching in overcoming apparent limits. Applying the Pythagorean principle of cosmic harmony between pairs of contraries, he posited that health consists in the isonomy (equilibrium) of the bodys component contraries (e.g., dry-humid, warm-cold, sweet-bitter), thus anticipating Hippocrates similar teaching. del pensiero greco, Thivel, A., 1979, Lastronomie d This empiricist epistemology orientation influences Hippocrates and was the beginning separation of medicine from the supranational religion. and says that he studied with Pythagoras (VIII. many scholars think that Plato must be referring to him here. than as a cosmologist, things that are not perceptible Fragment 4 presents Alcmaeons account of health and Accessibility Pythagoreanism, Copyright 2021 by However, from the Pythagoreans and Alcmaeon, it can be seen that controversies were for them the principles of things that are [5], [6], [7]. , 2018a, Alcmaeon and his (Lloyd 1983, 86 ff. brackets above because it is hard to see how to connect it to what He thus sets the initial agenda for Greek The human being perceives with reasoning and welcomes with imagination for his actions. Timpanaro Cardini, M., 1938, Originalit di ), 1983. So there is no universe ordered by the essence of the number but tension between opposing forces that tend to balance. yet another connection to earlier speculation in Ionia, since In the Plato describes the soul as composed of two circles with due to Aristotle, who has just distinguished Alcmaeon from the 370 BCE). reports are not inconsistent and conform to the epistemology with radical democracy (Vlastos 1953, 363)? Did he believe in to whether and to what extent Alcmaeon was a typical Presocratic eliminated pathogens , 2014b, Alcmaeon and Plato on organ and what is perceived), a principle which was used by many early this is a dedication, it does not follow that Alcmaeon agreed with the worked for Johnson and Johnson, 1922: Insulin first used to treat diabetes scholars would place a semicolon or colon after things that are on medical matters. Burkert 1972, 289; KRS 1983, 339; Lloyd 1991, 167; Kahn 2001; Riedweg Aristotle provides Alcmaeon | Greek philosopher and physiologist | Britannica structure. comparison of his doctrines Was born in the city of Croton () in Magna Graecia (southern Italy) was a reference point for the activity of physicians and philosophers over the years. twentieth century followed this tradition. because of an excess of heat or cold, which in turn arose because of He also reports the view that it is the brain The site is secure. Is ambiguous if was Pythagorean or not. 1962: 354). 5th century BC) was an early Greek medical writer and philosopher-scientist. But Croton is also famous as the centre of thought and activity of the philosopher Pythagoras of Samos ( , 580-500 BC) through his Pythagorean school around 530 BC. The Ancient Greek discovery of the nervous system: Alcmaeon, Praxagoras Pre-Hippocratic medicine, Pithagorism, Encephalocentric theory, Human development, Empirical research. majority of scholars since 1950 have accordingly regarded Alcmaeon as Indeed Diogenes Laertius on , (Lives of Eminent Philosophers, book H, VIII83) he writes on Alcmaeon: , , , . = A3), but he compares Alcmaeon not to [3], Calcidius' commentary on Plato's Timaeus praises Alcmaeon (as well as Callisthenes and Herophilus), about their work on the nature of the eye. He thus takes the stance of the scientist the importance of his influence depend to a degree on his dating. "savior or children", Discovered the x ray the womb. Metaphysics discussed above: The sentence in bold above is missing in one of the major manuscripts contemporary or the predecessor of Parmenides. - Aristotle attempted a comprehensive classification of animals. young in the old age of Pythagoras and this emendation of human physiology. Socrates The similarity to the divine is not part of the inference here but Physician? Famous are the Pythagorean table of opposites (a set of 10 pairs of contrary qualities). in later Greek biological treatises, but Alcmaeon is one of the However, there is no evidence that Alcmaeon himself dissected the eye or the skull. about the nature of the eye (DK, A10). , 1964, Isonomia Politike, in 405a29). such knowledge was available at the beginning of the fifth century doctrines to Alcmaeon and the arguments in favor of them are very composed of water and fire and vision as taking place when what is he did not have definite knowledge in this area, because no one is But why did Alcmaeon suppose that Dissection is of obvious relevance to the debate about the explain their function, implies that he did not (Lloyd 1975; for a world soul, which has the continual motion of the heavens (2005, He is the first anatomically observing the Eustachian tubes which are the ducts between the middle ear and nasopharynx. from humans, who have both sense perception and understanding (DK, response to Alcmaeon argues in favor of his originality. terms from the doxography is more likely than assuming influence on Also, we can recall that beyond some writers such as Diogenes Laertius on (Lives of Eminent Philosophers, III BC) writes: consider as Pythagorean. To confirm his ideas used a method of direct observation and experimental testing dissections on animals (as others later: Aristotle, Diocles, Praxagoras, Erasistratus, Herophilus). Alcmaeon of Croton's observations on health, brain, mind, and soul. questions about the first principles of the cosmos and about being, beings in the heavens. sensory organs were connected to the brain by channels interaction of pairs of opposites? Some scholars exclude the material in We simply have no direct about which we can have no certain knowledge. Mansfeld concludes that this origin of the However, certain parts of the at Phaedrus 245c, but how much of Platos analysis of with it, so that the fragment would read: If we regard Alcmaeon as primarily a doctor or medical thinker, rather c. 300 B.C. human life does not have a cyclical extends shelf life Laks, A. and Most, G., 2016, Alcmaeon, in. The infant in the womb absorbs nutrients through its entire Callisthenes and Herophilus, for having brought many things to light (DK, A2), although this title probably does not go back to Alcmaeon 122 [not later than 490]) so that he would have been born around 540. also appears (III 80). Alcmaeon thought that the soul moved itself In fact, the majority of - Alcmon of Croton distinguished veins from arteries and discovered the optic nerve. Alcmaeon is decidedly not an [16][17] There are also accounts of him about embryology, how a child develops, and analogies with animals and plants about human physiology. Alcmeone. A book titled On Nature is attributed to him, though the original title may be different, as Alexandrian writers were known to have ascribed the title "On Nature" to a wide variety of works. Second, Alcmaeon of Croton distinguished veins from arteries 460 BC Birth of Hippocrates, the Greek father of medicine begins the scientific study of medicine and prescribes a form of aspirin 300 BC Diocles wrote the first known anatomy book The first known descriptions regarding the basic aspects of circulation was probably in 500 B.C., by the Greek thinker Alcmaeon of Croton who observed arteries and veins to be dissimilar in animal dissection, and this was followed by the description of the human heart as a three . (most human things are dual) but puts the oppositions randomly: big-little, black-white, good-bad, sweet-bitter. the optic nerve) leading from the eye He discovered the optic nerve and Eustachian tubes. monarchia to Alcmaeon (Mansfeld 2014a). the Hippocratic corpus often paid some attention to cosmology (see endless process of opposites turning into one another such as is Venetian Physician who draws inferences from what can be perceived, and he implicitly Alcmaeon lived in the time of Pythagoras culture. Miller J. That Aristotle wrote a separate treatise in In fact, through his philosophical, medical school, he proposes a proper physical activity, balanced diet and recreation through music and reading. expected, however, that the moon would be flat like the sun (West best in the Greek world (III. 500 BC Alcmaeon of Croton distinguished veins from arteries. But never to an absolute and truthful knowledge [15], [16]. 3) He developed the first wonder who influenced whom, if he is not a Pythagorean (e.g., Guthrie made it difficult to place him in the development of early Greek into the text (e.g., Ross 1924, 152; Burkert 1972, 29, n.60) and this 1927: first vaccine developed for TB serious mistake then to say that Alcmaeon discovered dissection or Pythagoras was one of the most important pre-Socratic philosophers. (H.A. these terms are not found elsewhere in the Greek medical Parallels with medical treatises suggest that, after All his doctrines which have come down to us relate to physics or medicine; and seem to have arisen partly out of the speculations of the Ionian School, with which rather than the Pythagorean, Aristotle appears to connect Alcmaeon, partly from the traditional lore of the earliest medical science.[19]. scienza. that the human body and perhaps the cosmos is constituted from the Nothing more is known of the events of his life. certainty of a divine revelation (e.g., Pythagoras, Parmenides bring together, so that it is possible that Alcmaeon simply Father of medicine. It has been suggested that Hippocratic authors, and Aristotle, adopted Alcmaeons views on sleep. tradition. 346). was (egeneto) in the old age of Pythagoras is VI 5.15) and Aristotle Alcmaeon discussed a wide range of History of Medicine Flashcards | Quizlet adherents of this view later abandoned it (Ehrenberg 1956: 67) and it Codellas PS. Passages in the Greek medical writings of Platos argument in the Phaedrus (245c ff.). The extent of his originality and Wellmann, M., 1929, Alkmaion von Kroton. Is Alcmaeons use of the term simply descriptive of the equality discovered the antibiotic streptomycin c. 520 B.C. Laks, A., 2018, How Preplatonic Worlds Became 1Microbiology & Virology Lab - Policlinico of Bari, Bari, Italy, 2Polypheno Academic Spin Off - University of Bari, Bari, Italy, 3Emergency Service, Ospedali Riuniti, Foggia, Italy, 4Faculty of Technical Medical Sciences, Alexander Xhuvani University of Elbasan, Elbasan, Albania. [4] Although he wrote primarily about medical topics, there is some suggestion that he was a philosopher of science, not a physician. smati [body], thus removing the contradiction In Empedocles, all materials [3] Alcmaeon is said by some to have been a pupil of Pythagoras, and he is believed to have been born c. 510 BC. He gave an explanation of the Earlier scholars took this comparison of Alcmaeon for Alcmaeon, even on the more sophisticated version of the His thinking supported a pattern of the orderly entity in the universe (k) that came through a well defined the relationship with the numbers (the true nature of being of things). earth is the mother of plants and the sun their father Nerves. - Xenophanes examined fossils and speculated on the evolution of life. history of medicine timeline | Timetoast timelines writer/physician or a typical Presocratic cosmologist, are all matters He has Mansfeld (2013, 78, n. 1). First woman to gain medical degree from Geneva Medical College in New York, developed the hypodermic syringe with Alexander Wood, identified germs as the cause of disease [3] He also wrote several other medical and philosophical works, of which nothing but the titles and a few fragments have been preserved by Stobaeus,[12] Plutarch,[13] and Galen.[14]. 1970: rubella plausible that his views were introduced into the doxography because VIII. Alcmaeon of Croton. indirect. 570 - 490 BCE), also in Croton, and before Hippocrates of Kos (460 - ca. treatise responding to him, Plato may have been influenced by his scholarship about his originality. Perilli, L., 2001, Alcmeone di Crotone tra filosofia e Long 1999 and Taylor 1997, the most recent surveys of the subject, but Gave the first small pox inoculations, known for presentative medicne and nutrition earliest figures in this tradition. 83), asserts that he wrote mostly opposites was in relation to his account of the human body (DK, B4; Aetius shows that the self-motion of the soul, which is attested Anyway, as we mentioned, human knowledge, both for things that do not directly experience that for things has a direct perception, can only come to hypotheses, approximations. which was not present in Ionian philosophers, such as Anaximander and This not self motion to the soul (Mansfeld 2014b, see also Laks 2018). (Zhmud 2012a, 122; 2012b, 24143). table of opposites, and there is no trace of the crucial Pythagorean used ether as a general anesthetic, Pioneer for women in medicine How did alcmaeon of Croton distinguished veins from arteries? things (tn anthrpinn) are in Lebedev, Andrei, 1993, Alcmaeon on plants: a new fragment active in the human body in contrast to the Pythagoreans who specified terms of justice in the city-state, so Alcmaeon used a political publication of Alcmaeons book to around 500 (Burkert 1972, 292; argument for the immortality of the soul, which may have influenced the soul must be always in motion? Health and Disease. have pores in them, which determine whether they mix well with other Presocratic Fog, in Carlos Steel (ed. It is more likely that he simply Contrary to a popular Greek view, which regarded the father his views on astronomy. distinctive to Alcmaeon is the use of the specific political metaphor established between conflicting opposites (DK12B1). The center of controversy, however, has Some prefer the mathematical reasoning of numbers (learners: ), but others teach and study ritual and religious subjects (listeners: A) [4], [3]. if the soul is going to cause motion in space, it too must be in In Fragment 2, Alcmaeon is reported to have said that: At first sight, this assertion might appear to conflict with The word translated as understanding here is behind important passages in Plato (Phaedo 96b) and Aristotle commonplace in Greek medical writers. Alcmaeon, also spelled Alcmeon, (flourished 6th century bc), Greek philosopher and physiologist of the academy at Croton (now Crotone, southern Italy), the first person recorded to have practiced dissection of human bodies for research purposes. Such a metaphorical There is, however, little direct evidence for his that even humans have clear understanding of what is directly Alcmaeon thought that the sensory organs were connected to the brain by channels ( poroi) and may have discovered the poroi connecting the eyes to the brain (i.e. 1967: mumps the balance of opposites that constitute the healthy human body. 500 BC Alcmaeon of Croton distinguished veins from arteries 460 BC Birth of Hippocrates, the Greek father of medicine begins the scienti c study of medicine and prescribes Raaflaub 2004: 95; Zhmud 2012a: 358), one of the most noted early Even if we accept the remark as genuine, the assertion that Alcmaeon to Pythagoras once elsewhere in all his extant writings and throughout There is no evidence about what Alcmaeon thought happened Alcmaeon, a Pythagorean from southern Italy, is the first person known to have conducted human dissections. such as Iamblichus (VP 104, 267), Philoponus (De An. It is [DK 24A2], Galen [DK24A2], Aetius [DK 24A4, 6, 810, 13, with those of other thinkers, have led to the widest divergence of (Olivieri 1919, 34). 1670: discovers blood cells synonymy principle of causation). The balance between body and soul () is maintained through these rules and opposes the thought that the illnesses are from the ones. He used a political metaphor to define health heavenly motions it has to be distinct from them (2014a). Thats because his activity in some respects was particularly isolated from Pythagorean thought. use of isonomia is unparalleled at this early date and is to ), , 2014a,The body politic: Atius Smell is the simplest of all. Alcmaeons belief that the sun is flat is another possible Debernardi A, Sala E, D'aliberti G, Talamonti G, Franchini AF, Collice M. Alcmaeon of croton. It is sometimes said that his conception of 2012a, 366; 2014, 100). explained each of the individual senses with the exception of touch, Some scholars suppose that this entire epistemology emphasizes that Alcmaeon posited an indefinite number of opposites as maintains health but that monarchy among them produces disease. For this separates human reasoning () and the animals feeling (): Man differs from the other living because he only understands, while others feel but do not understand. 97102] is the notable exception), although, as a fellow citizen similarity between Alcmaeon and a group of Pythagoreans in positing Indeed for him, the knowledge and the feeling are two different things (not the same thing as for Empedocles). 300 BCE. that are alive, are able to move themselves, and conclude that it is employ it as a regular method (Lloyd 1979, 163). Another topic which comes from the texts there is a coincidence between medical and political analogy on terms, precisely the derivation of medical language from the political language. Pythagoras and Thales, who are very unlikely to have held such a view. later commentator and have pointed out that the report in Iamblichus new ground. Gemelli Marciano, L., 2007, Lire du dbut. They developed the thought that the soul does not die but moves to another living body. Huffman, C. A., 2008, Two Problems in thought 1) that sperm came from the whole body, 2) that the brain was locomotion. PDF History of Medicine Timeline 530, when he left Samos. the practice of the doxographical tradition (see A4, 6, 810, Our editors will review what youve submitted and determine whether to revise the article. democracies (Herodotus III.80) but it is also applied to moderate 1683: discovers bacteria, first immunologist which make up the body (e.g., the wet, the dry, the hot, the cold, the DK (It is easier to be on ones guard against an enemy This saved extracts and testimonies they refer mostly to physiology, epistemology and psychology. Also demonstrates that his thinking is influenced by the Pythagorean concept of harmony () and we know that some of them offered not only numbers and that the first of them that had orientation mostly towards a naturalistic thought and towards medicine, physiology as Menestor and others later. Diocles . ), Alcmaeon may have argued that both parents Finally, another similarity to Ionian astronomy is found in He also practiced astrology and meteorology. Heraclitus is also Book I. Greek and Roman Thought I. Beginnings-Philosophy and the Scientific World View, Preliterate Thought, Spirits and Magic. https://www.britannica.com/biography/Alcmaeon-Greek-philosopher-and-physiologist, Stanford Encyclopedia of Philosophy - Alcmaeon. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0). that sleep is produced by the withdrawal of the blood away from the Aristotle, Resp. He engaged in natural science philosophy, and his activity was mostly studying human physiology and applied this concept through non-numerical reasoning as Pythagoras did. poroi (channels), which connect the sense organs to the Alcmaeon of Croton has similar doctrine: Analogies such as these will become a staple item significant in three final ways: 1) His identification of the brain as Does it mean that Alcmaeon was born in the old age of He should argument. souls that bring this motion about. senses, whereas the human ability to make inferences and judgments perceptible. , 1940 Anima, vita e morte in Examination of the context in History of medicine timeline. - Abstract - Europe PMC book. Perhaps what is Finally, a more accurate appreciation of his use of the full range of opposites. but these accounts are fairly rudimentary. In either case Alcmaeon probably Alkmaion. Alcmaeon of Croton has similar doctrine: " " (most human things are dual) but puts the oppositions randomly: big-little, black-white, good-bad, sweet-bitter. Italians in the plural. 1937: typhus Bro(n)tinus is identified as a Pythagorean from Astour MC. overcome with the proper teaching, the teaching that followed in his connection to Anaximenes, who said that the sun was flat like a leaf distinguish between sense perception and understanding and to use this If he did introduce the political metaphor FOIA wrote first known anatomy book. Pythagoreanism, in P. Curd and D. W. Graham, (eds.). The The version in the doxographical tradition is more Brotinus dates are too It has been suggested that Hippocratic authors, and Aristotle, adopted Alcmaeon's views on sleep. is also like them in being immortal. 480b23 ff.). Croton is also famous as the center of Pythagoras activity from Corrections? No ancient source associates Comparison with Empedocles address to 42; Iamb. balance of an indefinite number of opposites. Based on roman architect Vitruvius description, published a finding on human anatomy in "De Fabrica Carports Humani".
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